<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BR1053 BR1053 Brazil 2001 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14KR, I15V, G16E, K20R, M36I, N37K, R41N, R57K, Q61N, I72T, L89I, C95S, N98K  
>BR1053| codons 1-99
PQITLWQRPLVTIRVEGQLREALLDTGADDTVLEEIKLPGNWKPKMIGGIGGFIKVKQYD
NILIEICGHKATGTVLVGPTPVNIIGRNILTQIGSTLKF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K122E, I135L, S162C, K173I, Q174K, Q207E, R211K  
>BR1053| codons 36-222
EICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIP
HPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKG
SPAIFQCSMTKILEPFRIKNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFT
TPDKKHQ

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005