Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TVSP1 | TVSP1 | Brazil | 1999 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 43 |
| 2 | 3TC+D4T | 22 |
| 3 | 3TC+D4T+RTV | 39 |
| 4 | 3TC+D4T+NFV | 8 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215F | K22N, V35T, E44K, I135V, S162C, E169A, K173A, Q174K, Q207E, R211K, V245Q, E248D, A272P, T286A, V292I, I293V, E297T |
| >TVSP1| codons 1-324 PISPIETVPVKLKPGMDGPKVNQWPLTEEKIKALTEICTELEKKGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILAPFRAKNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTTEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | T12A, Q18L, L19I, K20R, E35D, M36I, R41K, R57K, Q61H, L63P, I72T |
| >TVSP1| codons 1-99 PQITLWQRPLVAIKIGGLIREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVKQYD HIPIEICGHKATGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Brindeiro, PA | Testing genotypic and phenotypic resistance in human immunodeficiency virus type 1 isolates of clade B and other clades from children failing antiretroviral therapy. | J Clin Microbiol, 2002 |