Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TVGG3 | TVGG3 | Brazil | 1999 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 165 |
| 2 | AZT+DDI | 9 |
| 3 | 3TC+AZT | 113 |
| 4 | 3TC+D4T+NFV | 30 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IV, V82VA | L10LV, I15V, L19I, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, H69Y, I72T, L89M |
| >TVGG3| codons 1-99 PQITLWQRPVVTIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVKQYD NIVIDICGYKATGTVLVGPTPANIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, M184V | K219KQ | K49R, V118I, K122E, I135T, E169D, F214L, V245T, A272P, K281R, T286A, I293V, E297K |
| >TVGG3| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDQKHQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTEVVPLTKEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Brindeiro, PA | Testing genotypic and phenotypic resistance in human immunodeficiency virus type 1 isolates of clade B and other clades from children failing antiretroviral therapy. | J Clin Microbiol, 2002 |