Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TVGG27 | TVGG27 | Brazil | 1999 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+RTV | 4 |
| 2 | 3TC+D4T+NFV+NVP | 26 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T215Y | K70S, V75S | V106A, Y181C | V35T, E44D, K122E, E169D, K173T, Q174K, I178L, Q197E, T200A, E203K, Q207A, H208Y, R211K, K223Q, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297A | N306D |
| >TVGG27| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKDGKISKIGPENPYNTPV FAIKKKNSTSWRKLSDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRTKNPDLVI CQYMDDLYVGSDLEIGEHRAKIKELRAYLLKWGFYTPDKKHQQEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAEDREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | L10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, L89I |
| >TVGG27| codons 1-99 PQITLWQRPIVTIKVGGQLREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFVKVKQYD NILIEICGHKAIGSVLVGPTPANIIGRNIMTQIGCTLNF |
References
| Author | Title | Citation |
| Brindeiro, PA | Testing genotypic and phenotypic resistance in human immunodeficiency virus type 1 isolates of clade B and other clades from children failing antiretroviral therapy. | J Clin Microbiol, 2002 |