<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TVGG18 TVGG18 Brazil 1999 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC 43

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I15V, E35D, M36I, R41K, R57K, D60E, Q61D, L63T, I93L  
>TVGG18| codons 1-99
PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE
DITIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215F       K20R, V35T, T39A, E40D, K49R, I135V, E169D, K173T, Q174R, I178L, T200A, Q207E, H208Y, R211K, V245Q, E248D, A272P, K277R, T286A, A288T, E291D, V292I, I293V, E297V, S322T  
>TVGG18| codons 1-324
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICADLEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRTRNPDLVI
YQYVDDLYVGSDLEIGQHRAKIEELREYLLKWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKTLTDIVPLTVEAE
LELAENREILKEPVHGVYYDPTKD

References
Author Title Citation
Brindeiro, PA Testing genotypic and phenotypic resistance in human immunodeficiency virus type 1 isolates of clade B and other clades from children failing antiretroviral therapy. J Clin Microbiol, 2002