Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BR8 | BR8 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 17 |
| 2 | D4T+ 3TC | 86 |
| 3 | D4T+ DDI+ NFV | 43 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L10I, T12I, I13V, I15V, K20T, E35D, M36I, R41K, K45T, L63P, I64IV, I85IV |
| >BR8| codons 1-99 PQITLWQRPIVIVKVGGQLTEALLDTGADNTVLEDINLPGKWKPTMIGGIGGFIKVRQYD QIPVEICGHKAIGTVLVGPTPVNIVGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, L210W, T215Y | K219R | K20R, K32R, T39S, V60I, V90I, V118I, I142V, E169D, H208Y, R211K, K223Q |
| >BR8| codons 1-233 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIRALVEICSELEKEGKISKIGPENPYNTPI FAIKKKNSTKWRKVVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTPDRKHQQEPPFLWMGYE |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |