Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BR38 | BR38 | Brazil | 2001 | HIV1 | B + F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 8 |
| 2 | DDI+ AZT | 56 |
| 3 | NFV+ DDI+ AZT | 50 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I15V, K20T, E35D, M36I, N37D, P39Q, R41K, R57K, D60E, Q61D, L89I |
| >BR38| codons 1-99 PQITLWQRPLVTIKVGGQLTEALLDTGADDTVLEDIDLQGKWKPKMIGGIGGFIKVKQYE DILIEICGHKAIGTVLVGPTPVNIIGRNIMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | E53D, K104R, V118I, D123E, I135T, E169D, K173A, Q174K, Q207E, R211K, F214L |
| >BR38| codons 36-225 EICTELEKEGKISKIGPDNPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIP HPAGLKKKRSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILDPFRAKNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGLY TPDKKHQKEP |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |