Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JPN24 | JPN24 | Japan | 2000 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 48 |
| 2 | None | 1 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33F | T12S, I13V, M36I, N37D, R41K, H69K, K70R, L89M, I93L | K45KE |
| >JPN24| codons 1-99 PQITLWQRPLVSVKIGGQLKEALLDTGADDTVFEEIDLPGKWKPEMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, K11T, I31T, V35T, T39KQ, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, T200TA, I202L, Q207A, R211S |
| >JPN24| codons 1-243 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKTKALTEICQEMEEEGKISKIGPENPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMVI YQYMDDLYVGSDLEIGQHRAKLEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQP |
References
| Author | Title | Citation |
| Ariyoshi, K | Patterns of point mutations associated with antiretroviral drug treatment failure in CRF01_AE (subtype E) infection differ from subtype B infection. | JAIDS, 2003 |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |