Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JPN21 | JPN21A | Japan | 1999 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC+ 3TC | 17 |
| 2 | IDV+ D4T+ 3TC | 77 |
| 3 | D4T+ 3TC+ NFV | 47 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, N88S | L10F, T74TP, L89V | K20I, M36I, L63LP, H69K, I85V, I93L |
| >JPN21A| codons 1-99 PQITLWQRPFVTIKIGGQLIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFIKVRQYD QIPIEICGKKAIGPVLVGPTPVNIVGRSVLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DN, M184V | E6N, V21VI, I31IT, V35T, T39K, K43E, T69TN, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, V245E | S162SGIV |
| >JPN21A| codons 1-253 PISPINTVPVKLKPGMDGPKIKQWPLTEEKTKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKNSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQVSMTKILEPFRIKNPEMVI YQYVDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWT |
References
| Author | Title | Citation |
| Ariyoshi, K | Patterns of point mutations associated with antiretroviral drug treatment failure in CRF01_AE (subtype E) infection differ from subtype B infection. | JAIDS, 2003 |