<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
JPN6 JPN6 Japan 1998 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ D4T+ NFV 1

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L24LI I13V, I15V, E35D, M36I, R41K, H69K, L89M  
>JPN6| codons 1-99
PQITLWQRPLVTVKVGGQLKEALIDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, K20KR, V35T, T39K, K43E, V60VI, I135T, K166R, K173V, Q174K, D177E, V179I, T200A, Q207A, R211S, K238R, V245N  
>JPN6| codons 1-266
PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRVKNPEIII
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT
VQPINLPEKDSWTVNDIQKLVGKLNW

References
Author Title Citation
Ariyoshi, K Patterns of point mutations associated with antiretroviral drug treatment failure in CRF01_AE (subtype E) infection differ from subtype B infection. JAIDS, 2003