Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JPN30 | JPN30 | Japan | 2000 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | 7 |
| 2 | 3TC+ D4T | 15 |
| 3 | D4T+ 3TC+ NFV | 71 |
| 4 | D4T+ DDI+ EFV | 8 |
| 5 | D4T+ 3TC+ EFV | 10 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10V, I13V, K20T, E35D, M36I, R41K, H69K, K70R, T74S, L89I |
| >JPN30| codons 1-99 PQITLWQRPVVTVKIGGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGSVLVGPTPVNIIGRNIMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A62V, V75S, T215TN | K103N | V108VI | K11T, V35T, T39K, K43E, S68G, T69S, K102R, D121H, K122E, D123S, S162N, Q174K, D177E, I178M, I180V, G196E, T200A, Q207A | K220KN, K223KN |
| >JPN30| codons 1-230 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FVIKKKDGSKWRKLSDFRELNKRTQDFWEVQLGIPHPAGLKRNKSVTILDVGDAYFSVPL HESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKKNPEMVV YQYVDDLYVGSDLEIEQHRAKIEELRAHLLRWGFNTPDKNHQNEPPFLWM |
References
| Author | Title | Citation |
| Ariyoshi, K | Patterns of point mutations associated with antiretroviral drug treatment failure in CRF01_AE (subtype E) infection differ from subtype B infection. | JAIDS, 2003 |