Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JPN28 | JPN28 | Japan | 2000 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | 72 |
| 2 | D4T+ 3TC+ NFV | 80 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210LW, T215F | E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, I178IM, V179VI, Q207A, R211S, K238R, V245E |
| >JPN28| codons 1-253 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKELEEEGKISKIGPENPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMII YQYVDDLYVGSDLEIGQHRTKIEELRAHLWSWGFFTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSWT |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, N88S, L90LM | L10LF | I13V, K20T, E35D, M36I, R41K, H69K, K70R, A71AT, L89X |
| >JPN28| codons 1-99 PQITLWQRPFVTVKIGGQLTEALLDTGADDTVLEDINLPGKWKPKIIGGIGGFIKVRQYD QILIEICGKRTIGTVLVGPTPVNIIGRSXMTQIGCTLNF |
References
| Author | Title | Citation |
| Ariyoshi, K | Patterns of point mutations associated with antiretroviral drug treatment failure in CRF01_AE (subtype E) infection differ from subtype B infection. | JAIDS, 2003 |