Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JPN27 | JPN27A | Japan | 2000 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G17E, K20R, E35D, M36I, R41K, R57RK, I62IV, H69K, L89M |
| >JPN27A| codons 1-99 PQITLWQRPLVTVKIGEQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, V35T, E36ED, T39KR, K43E, V60I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238KR, V245E |
| >JPN27A| codons 1-252 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTDICREMEEEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMVI YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSW |
References
| Author | Title | Citation |
| Ariyoshi, K | Patterns of point mutations associated with antiretroviral drug treatment failure in CRF01_AE (subtype E) infection differ from subtype B infection. | JAIDS, 2003 |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |