Isolate Data
Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
MAK-1700 | 1700481 | U.K. | 1998 | HIV1 | B | Plasma | None |
Treatment History
Order | Regimen | Weeks |
1 | AZT+ 3TC+ ABC | 47 |
RT Sequence
NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
L74V, M184V | K20R, V35I, K64KR, K101Q, K103R, I135K, K173E, Q174R, R211K | D86S |
>1700481| codons 20-230 RVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPVFAIRKKDSTKWRKVVDFRE LNKRTQSFWEVQLGIPHPAGLQKRKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSKNNET PGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRERNPDIVIYQYVDDLYVGSDLEIGQHR TKIEELRQHLLKWGFTTPDKKHQKEPPFLWM |
References
Author | Title | Citation |
Ait-Khaled, M | Mutations in HIV-1 reverse transcriptase during therapy with abacavir, lamivudine, zidovudine in HIV-1 infected adults with no prior antiretroviral therapy. | Antivir Ther, 2002 |
Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |