Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MAK-1755 | 1755481 | U.K. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT | 18 |
| 2 | NFV+ ABC+ 3TC | 1 |
| 3 | ABC+ 3TC+ D4T+ NFV | 15 |
| 4 | D4T+ ABC+ 3TC | 6 |
| 5 | IDV+ D4T+ ABC+ 3TC | 2 |
| 6 | D4T+ ABC+ 3TC | 5 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K20R, V35IR, K103R, I135AT, I178M, V179I |
| >1755481| codons 20-230 RVKQWPLTEEKIKALREICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRE LNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSTNNET PGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMIIYQYVDDLYVGSDLEIGQHR TKIEELRQHLLRWGFTTPDKKHQKEPPFLWM |
References
| Author | Title | Citation |
| Ait-Khaled, M | Mutations in HIV-1 reverse transcriptase during therapy with abacavir, lamivudine, zidovudine in HIV-1 infected adults with no prior antiretroviral therapy. | Antivir Ther, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |