Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MAK-1751 | 1751481 | U.K. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ ABC | 47 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y115F, M184V | R125K, I142V, S162A, D177E, G196E |
| >1751481| codons 20-230 KVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRE LNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAFFSVPLDKDFKKYTAFTIPSINNET PGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPEIVIYQYVDDLYVGSDLEIEQHR TKIEELRQHLLRWGFTTPDKKHQKEPPFLWM |
References
| Author | Title | Citation |
| Ait-Khaled, M | Mutations in HIV-1 reverse transcriptase during therapy with abacavir, lamivudine, zidovudine in HIV-1 infected adults with no prior antiretroviral therapy. | Antivir Ther, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |