Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MAK-4296 | 4296481 | U.K. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | ABC+ AZT+ 3TC | 47 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | E138EK | V90I, K173E, Q207E |
| >4296481| codons 20-230 KVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRE LNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNKT PGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFREQNPDIVIYQYVDDLYVGSDLEIGQHR TKIEELREHLLRWGFTTPDKKHQKEPPFLWM |
References
| Author | Title | Citation |
| Ait-Khaled, M | Mutations in HIV-1 reverse transcriptase during therapy with abacavir, lamivudine, zidovudine in HIV-1 infected adults with no prior antiretroviral therapy. | Antivir Ther, 2002 |
| Rhee, SY | Distribution of human immunodeficiency virus type 1 protease and reverse transcriptase mutation patterns in 4,183 persons undergoing genotypic resistance testing. | AAC, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |