<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
3PoBV 3PoBV66 U.S. 1994 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 66

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A L24I L10I, I62V, L63Q, A71V, I93L  
>3PoBV66| 37 | codons 1-99 | clone 37
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV66| 39 | codons 1-99 | clone 39
PQITLWQRPIVTIKIGGQLKEALIDTGADDTVLEEMNLPGRWKPKIIGGIGGFVKVRQYD
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV66| 40 | codons 1-99 | clone 40
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEKMNLPGGWKPKLIGGIGGFVKVRQYD
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV66| 41 | codons 1-99 | clone 41
PQITLWQRPIVTIKIGGRLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV66| 42 | codons 1-99 | clone 42
PQITLWQRPIVTIKIGGQLKEALIDTGADDTVLEEMNLPGRWKPKIIGGIGGFVKVRQYD
QVQIEICGHKVIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV66| 43 | codons 1-99 | clone 43
PQITLWQRPIVTIKIGGQLKEALIDTGADDTVLEEMNLPGRWKPKIIGGIGGFVKVRQYD
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV66| 45 | codons 1-99 | clone 45
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV66| codons 1-99
PQITLWQRPIVTIKIGGQLKEALIDTGADDTVLEEMNLPGRWKPKIIGGIGGFVKVRQYD
QVQIEICGHKVIGTVLVGPTPANIIGRNLLTQLGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005