Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ALD-pt18 | ALD-pt18 | Australia | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NNRTI|NRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I84V, L90M | L10F, G73S | R57K, L63P, A71V |
| >ALD-pt18| codons 1-99 PQITLWQRPFVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVKQYD QIPIEICGHKVISTVLVGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74LI, M184V, L210W, T215Y | V75VA | K103KNRS, G190GA | T39A, K43E, E44D, R83K, K102Q, V118I, K122E, S162Y, D177E, E203D, H208Y, R211K, H221HY, V245E, T286A, E297K |
| >ALD-pt18| codons 1-320 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEEDGKISKIGPENPYNTPV FAIKKKNSTKWRKIADFRELNKKTQDFWEVQLGIPHPAGLKQSKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPEIVI YQYVDDLYVASDLEIGQHRTKIDELRQYLWKWGFYTPDKKYQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYD |
References
| Author | Title | Citation |
| Dunne, AL | Comparison of genotyping and phenotyping methods for determining susceptibility of HIV-1 to antiretroviral drugs. | AIDS, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |