Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 3PoBV | 3PoBV37 | U.S. | 1994 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 37 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, V82A | L10I, I62V, L63Q, I93L |
| >3PoBV37| 19 | codons 1-99 | clone 19 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF >3PoBV37| 20 | codons 1-99 | clone 20 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF >3PoBV37| 21 | codons 1-99 | clone 21 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQND QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF >3PoBV37| 22 | codons 1-99 | clone 22 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF >3PoBV37| 23 | codons 1-99 | clone 23 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF >3PoBV37| 24 | codons 1-99 | clone 24 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF >3PoBV37| 25 | codons 1-99 | clone 25 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF >3PoBV37| 26 | codons 1-99 | clone 26 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF >3PoBV37| 27 | codons 1-99 | clone 27 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QVQIEICGHKAIGTVSVGLTPANIIGRNLLTQLGCTLNF >3PoBV37| 28 | codons 1-99 | clone 28 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF >3PoBV37| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |