<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
3PoBV 3PoBV37 U.S. 1994 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 37

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, V82A   L10I, I62V, L63Q, I93L  
>3PoBV37| 19 | codons 1-99 | clone 19
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKLIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF
>3PoBV37| 20 | codons 1-99 | clone 20
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF
>3PoBV37| 21 | codons 1-99 | clone 21
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQND
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV37| 22 | codons 1-99 | clone 22
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV37| 23 | codons 1-99 | clone 23
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV37| 24 | codons 1-99 | clone 24
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV37| 25 | codons 1-99 | clone 25
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF
>3PoBV37| 26 | codons 1-99 | clone 26
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>3PoBV37| 27 | codons 1-99 | clone 27
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QVQIEICGHKAIGTVSVGLTPANIIGRNLLTQLGCTLNF
>3PoBV37| 28 | codons 1-99 | clone 28
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF
>3PoBV37| codons 1-99
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QVQIEICGHKAIGTVLVGPTPANIIGRNLLTQLGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005