Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ALD-pt13 | ALD-pt13 | Australia | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NNRTI|NRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | I15V, E35D, M36MI, N37E, K45KQ, I62IV, L63P, I72IM, I93L |
| >ALD-pt13| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADNTVLEDIELPGRWKPQMIGGIGGFIKVRQYD QVPIEICGHKAMGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L210W, T215Y | K20R, R83K, V118VI, I135V, G196E, E203K, Q207E, R211K, A272P, K277R, I293IV, E297K |
| >ALD-pt13| codons 1-320 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIEQHRTKIKELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTKEAE LELAENREILKEPVHGVYYD |
References
| Author | Title | Citation |
| Dunne, AL | Comparison of genotyping and phenotyping methods for determining susceptibility of HIV-1 to antiretroviral drugs. | AIDS, 2001 |
| Rhee, SY | Distribution of human immunodeficiency virus type 1 protease and reverse transcriptase mutation patterns in 4,183 persons undergoing genotypic resistance testing. | AAC, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |