<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
3PoBV 3PoBV33 U.S. 1994 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 33

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L   L10I, L63Q, Q92R, I93L  
>3PoBV33| 58 | codons 1-99 | clone 58
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF
>3PoBV33| 59 | codons 1-99 | clone 59
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFTKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF
>3PoBV33| 60 | codons 1-99 | clone 60
PQITLWQRPIVTIKMGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF
>3PoBV33| 61 | codons 1-99 | clone 61
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQHD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF
>3PoBV33| 62 | codons 1-99 | clone 62
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF
>3PoBV33| 63 | codons 1-99 | clone 63
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF
>3PoBV33| 64 | codons 1-99 | clone 64
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIQIEICRHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF
>3PoBV33| 65 | codons 1-99 | clone 65
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGLIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF
>3PoBV33| codons 1-99
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005