Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ALD-pt11 | ALD-pt11 | Australia | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NNRTI|NRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | I13V, E35D, M36L, I62V, L63Q, I64V, T74S |
| >ALD-pt11| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADNTVLEDLNLPGRWKPKMIGGIGGFIKVRQYD QVQVEICGHKAIGSVLVGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210LW, T215Y | K122KE, K173Q, R211K, K238R, V245T, A272P, K277R, T286A, E297K |
| >ALD-pt11| codons 1-320 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRQQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDRWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYD |
References
| Author | Title | Citation |
| Dunne, AL | Comparison of genotyping and phenotyping methods for determining susceptibility of HIV-1 to antiretroviral drugs. | AIDS, 2001 |
| Rhee, SY | Distribution of human immunodeficiency virus type 1 protease and reverse transcriptase mutation patterns in 4,183 persons undergoing genotypic resistance testing. | AAC, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |