Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ALD-pt3 | ALD-pt3 | Australia | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NNRTI|NRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90LM | E35ED, R41K, L63Q, I64V, V82I |
| >ALD-pt3| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMNLPGKWKPKMIGGIGGFIKVRQYD QIQVEICGHKAIGTVLVGPTPINIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | K103N | D123E, I135V, Q197E, Q207A, R211K, V245KN, L283I, A288AP, I293V, P294A, E297K |
| >ALD-pt3| codons 1-320 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGEHRTKIEELRAHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPINLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGTKPLTEVVALTKEAE LELAENREILKEPVHGVYYD |
References
| Author | Title | Citation |
| Dunne, AL | Comparison of genotyping and phenotyping methods for determining susceptibility of HIV-1 to antiretroviral drugs. | AIDS, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |