Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 3PoBV | 3PoBV29 | U.S. | 1994 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 29 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L | L10I, L63Q, Q92R, I93L |
| >3PoBV29| 1 | codons 1-99 | clone 1 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF >3PoBV29| 2 | codons 1-99 | clone 2 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF >3PoBV29| 3 | codons 1-99 | clone 3 PQITLWQRPIVTIKIGEQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTLVNIIGRNLLTRLGCTLNF >3PoBV29| 4 | codons 1-99 | clone 4 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF >3PoBV29| 5 | codons 1-99 | clone 5 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF >3PoBV29| 6 | codons 1-99 | clone 6 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF >3PoBV29| 7 | codons 1-99 | clone 7 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF >3PoBV29| 8 | codons 1-99 | clone 8 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF >3PoBV29| 9 | codons 1-99 | clone 9 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF >3PoBV29| 10 | codons 1-99 | clone 10 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF >3PoBV29| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTRLGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |