<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
3PoBV 3PoBV14 U.S. 1993 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 14

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    Q7K, L10I, R41K, I85V, I93L A28V
>3PoBV14| 2 | codons 1-99 | clone 2
PQITLWKRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILMEICGHKAIGTVLVGPTPVNIVGRNLLTQLGCTLNF
>3PoBV14| 9 | codons 1-99 | clone 9
PQITLWKRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIVGRNLLTQLGCTLNF
>3PoBV14| 12 | codons 1-99 | clone 12
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEKMNLPGRWKPKMIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>3PoBV14| 17 | codons 1-99 | clone 17
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEKMNLPGRWKPKMIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>3PoBV14| 33 | codons 1-99 | clone 33
PQITLWKRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIVGRNLLTQLGCTSNF
>3PoBV14| 36 | codons 1-99 | clone 36
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIVGRNLLTQLDCTLNF
>3PoBV14| 37 | codons 1-99 | clone 37
PQITLWKRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIVGRNLLTQLGCTLNF
>3PoBV14| 40 | codons 1-99 | clone 40
PQITLWKRPIVTIKIGGQLKEALLDTGVDDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIVGRNLLTQLGCTLNF
>3PoBV14| 51 | codons 1-99 | clone 51
PQITLWKRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIVGRNLLTQLGCTLNF
>3PoBV14| 53 | codons 1-99 | clone 53
PQITLWKRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIVGRNLLTQLGCTLNF
>3PoBV14| 54 | codons 1-99 | clone 54
PQITLWKRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIVGRNLLTQLGCTLNF
>3PoBV14| 59 | codons 1-99 | clone 59
PQITLWKRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIVGRNLLTQLGCTLNF
>3PoBV14| 60 | codons 1-99 | clone 60
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEKMNLPGRWKPKMIGGIGGFIKVRQYD
QIQIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>3PoBV14| 70 | codons 1-99 | clone 70
PQITLWKRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIVGRNLLTQLGCTLNF
>3PoBV14| codons 1-99
PQITLWKRPIVTIKIGGQLKEALLDTGVDDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIVGRNLLTQLGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005