<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
8LaBV 8LaBV48 U.S. 1994 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 48

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, V82A   L10I, I13V, K20M, M36I, L63P, I64V, H69Q R8P
>8LaBV48| 3 | codons 1-99 | clone 3
PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD
QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV48| 4 | codons 1-99 | clone 4
PQITLWQPPVVTVKIGGQLMEALLDTGADDTVLEEINLPGRWTPKMIVGIGGFVKVRQYD
QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV48| 5 | codons 1-99 | clone 5
PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD
QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV48| 6 | codons 1-99 | clone 6
PQITLWQPPIVTVKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFVKVRQYD
QVPVDICGHKAIGTVLIGPTPFNIIGRNLLTQIGCTLNF
>8LaBV48| 7 | codons 1-99 | clone 7
PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD
QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV48| 8 | codons 1-99 | clone 8
PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD
QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV48| 9 | codons 1-99 | clone 9
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD
QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF
>8LaBV48| 10 | codons 1-99 | clone 10
PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD
QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV48| 11 | codons 1-99 | clone 11
PQITLWQPPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD
QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF
>8LaBV48| codons 1-99
PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD
QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005