Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8LaBV | 8LaBV48 | U.S. | 1994 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 48 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, V82A | L10I, I13V, K20M, M36I, L63P, I64V, H69Q | R8P |
| >8LaBV48| 3 | codons 1-99 | clone 3 PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV48| 4 | codons 1-99 | clone 4 PQITLWQPPVVTVKIGGQLMEALLDTGADDTVLEEINLPGRWTPKMIVGIGGFVKVRQYD QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV48| 5 | codons 1-99 | clone 5 PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV48| 6 | codons 1-99 | clone 6 PQITLWQPPIVTVKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFVKVRQYD QVPVDICGHKAIGTVLIGPTPFNIIGRNLLTQIGCTLNF >8LaBV48| 7 | codons 1-99 | clone 7 PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV48| 8 | codons 1-99 | clone 8 PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV48| 9 | codons 1-99 | clone 9 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF >8LaBV48| 10 | codons 1-99 | clone 10 PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV48| 11 | codons 1-99 | clone 11 PQITLWQPPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF >8LaBV48| codons 1-99 PQITLWQPPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |