Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8LaBV | 8LaBV44 | U.S. | 1994 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 44 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, V82A | L10I, I13V, K20M, M36I, L63P, I64V, H69Q | T26A |
| >8LaBV44| 19 | codons 1-99 | clone 19 PQITLWQRPVVTVKIGGQLMEALLGTGADDTVLEEINLPGRWTPKMIVGIGGFVKVRQYD QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV44| 20 | codons 1-99 | clone 20 PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEKINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPASIIGRNLLTQIGCTLNF >8LaBV44| 21 | codons 1-99 | clone 21 PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV44| 22 | codons 1-99 | clone 22 PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV44| 23 | codons 1-99 | clone 23 PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV44| 24 | codons 1-99 | clone 24 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF >8LaBV44| 26 | codons 1-99 | clone 26 PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV44| 28 | codons 1-99 | clone 28 PQITLWQRPVVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QVPVEICGHKAMGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV44| 29 | codons 1-99 | clone 29 PQITLWQRPIVTVKIGGQLMEALLDAGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV44| 30 | codons 1-99 | clone 30 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF >8LaBV44| codons 1-99 PQITLWQRPIVTVKIGGQLMEALLDAGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |