Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8LaBV | 8LaBV39 | U.S. | 1994 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 39 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, V82A | L10I, V11A, I13V, K20M, M36I, L63P, I64V, H69Q |
| >8LaBV39| 91 | codons 1-99 | clone 91 PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV39| 92 | codons 1-99 | clone 92 PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIECTLNF >8LaBV39| 94 | codons 1-99 | clone 94 PQITLWQRPVDTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIRVRQYD QLPADICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF >8LaBV39| 95 | codons 1-99 | clone 95 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFVKVRQYD QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV39| 97 | codons 1-99 | clone 97 PQITLWQRPIATVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV39| 98 | codons 1-99 | clone 98 PQITLWQRPIATVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV39| 99 | codons 1-99 | clone 99 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF >8LaBV39| 100 | codons 1-99 | clone 100 PQITLWQRPIATVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV39| 101 | codons 1-99 | clone 101 PQVTLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF >8LaBV39| 102 | codons 1-99 | clone 102 PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV39| codons 1-99 PQITLWQRPIATVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |