<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
8LaBV 8LaBV35 U.S. 1994 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 35

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, G48V, V82A, L90M   L10I, I13V, K20M, M36I, L63P, I64V, H69Q  
>8LaBV35| 37 | codons 1-99 | clone 37
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWEPKIIGGIGGFIKVRQYD
QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF
>8LaBV35| 39 | codons 1-99 | clone 39
PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD
QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV35| 40 | codons 1-99 | clone 40
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFVKVRQYD
QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV35| 42 | codons 1-99 | clone 42
PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD
QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV35| 43 | codons 1-99 | clone 43
PQITLWQRPVVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD
QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV35| 44 | codons 1-99 | clone 44
PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEITLPGRWKPKMIVGIGGFIKVRQYD
QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV35| 46 | codons 1-99 | clone 46
PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKMIVGIGGFIKVRQYD
QIPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV35| 47 | codons 1-99 | clone 47
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD
QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF
>8LaBV35| 48 | codons 1-99 | clone 48
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD
QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF
>8LaBV35| codons 1-99
PQITLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWKPKIIVGIGGFIKVRQYD
QIPVEICGQKAIGTVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005