Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CU35 | CU35 | Cuba | 1999 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI+ SQV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, R41K, L63P, V77I, I93L |
| >CU35| codons 1-99 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K49R, K122E, I142V, E194K, T200A, K201I, Q207H, R211K | H198P |
| >CU35| codons 1-220 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLKIGQPRAIIEELRHHLLKWGFTTPDKK |
References
| Author | Title | Citation |
| Cuevas, MT | High HIV-1 genetic diversity in Cuba. | AIDS, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |