<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
8LaBV 8LaBV22 U.S. 1994 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 22

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54V, V82A   L10V, I62V, L63P, I64V, E65D  
>8LaBV22| 19 | codons 1-99 | clone 19
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD
QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV22| 20 | codons 1-99 | clone 20
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFVKVRQYD
QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV22| 21 | codons 1-99 | clone 21
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFVKVRQYD
QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV22| 22 | codons 1-99 | clone 22
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD
QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV22| 23 | codons 1-99 | clone 23
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD
QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV22| 24 | codons 1-99 | clone 24
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPG.RKPKIIGGIGGFIKVRQYD
QVPVDICGHKAIGTVLIGPTPVNIIGRNLMTKLGCTLNF
>8LaBV22| 25 | codons 1-99 | clone 25
PQITLWQRPVVAIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFVKVRQYD
QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV22| 26 | codons 1-99 | clone 26
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFVKVRQYD
QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV22| 27 | codons 1-99 | clone 27
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFVKVRQYD
QAPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV22| 29 | codons 1-99 | clone 29
PQITLWQRPVVTIKMGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFVKVRQYD
QAPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF
>8LaBV22| codons 1-99
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFVKVRQYD
QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005