Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 8LaBV | 8LaBV17 | U.S. | 1993 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 17 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, V82A | L10V, I62V, L63P, I64V, E65D |
| >8LaBV17| 19 | codons 1-99 | clone 19 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV17| 21 | codons 1-99 | clone 21 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV17| 25 | codons 1-99 | clone 25 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPVDICGHKAIGTVLIGPTPANIIGRNLLTQIGCTLNF >8LaBV17| 27 | codons 1-99 | clone 27 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD QVPVDICGHKAIGTVLIGPTPVNIIGRNLLTQIGCALNF >8LaBV17| 29 | codons 1-99 | clone 29 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV17| 31 | codons 1-99 | clone 31 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIDICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >8LaBV17| 32 | codons 1-99 | clone 32 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV17| 33 | codons 1-99 | clone 33 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV17| 34 | codons 1-99 | clone 34 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD QVPVDICGHKDIGTVLVGPTPANIIGRNLLTQIGCTLNF >8LaBV17| 35 | codons 1-99 | clone 35 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPVDICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF >8LaBV17| codons 1-99 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD QVPVDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |