<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CU75 CU75 Cuba 1999 HIV1 G PBMC None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC+ SQV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M F53L, L89V L10V, I13V, K20I, M36I, R41K, Q61E, H69K, K70R, A71V, T74S  
>CU75| codons 1-99
PQITLWQRPVVTVKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGLIKVRQYD
EILIEICGKRVIGSVLVGPTPVNIIGRNVMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y K219R     V35T, T39M, K43N, V60I, T69A, V118I, K122P, I135V, I142V, A158S, Q174A, D177E, I202V, Q207E, R211K  
>CU75| codons 1-221
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICMELENEGKISKIGPENPYNTPI
FAIKKKDSAKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DPDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKANPEIVI
YQYVDDLYVGSDLEIGQHRTKVEELREHLWKWGFYTPDRKH

References
Author Title Citation
Cuevas, MT High HIV-1 genetic diversity in Cuba. AIDS, 2002