Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 7DiBV | 7DiBV60 | U.S. | 1995 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 60 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82A, L90M | L33I, G73S | K14R, I62V, L63P, A71V, I93L |
| >7DiBV60| 65 | codons 1-99 | clone 65 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV60| 66 | codons 1-99 | clone 66 PQITLWQRPIVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEIRGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV60| 67 | codons 1-99 | clone 67 PQITLWQRPIVTIRIGGQLKEALLDTGADDTVIEEINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV60| 68 | codons 1-99 | clone 68 PQITLWQRPIVTIRIGGQLKEALLDTGADDTVIEEINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV60| 69 | codons 1-99 | clone 69 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV60| 70 | codons 1-99 | clone 70 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV60| 72 | codons 1-99 | clone 72 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV60| 73 | codons 1-99 | clone 73 PQTTLWQRPIVTVKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV60| 75 | codons 1-99 | clone 75 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV60| codons 1-99 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Wu, TD | Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. | J Virol, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |