Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 7DiBV | 7DiBV49 | U.S. | 1994 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 49 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82A, L90M | L33I, G73S | L10I, I62V, L63P, A71V, V77I, I93L |
| >7DiBV49| 1 | codons 1-99 | clone 1 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPATIIGRNLMTQLGCTLNF >7DiBV49| 2 | codons 1-99 | clone 2 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPRRWKPKMIGGIGGFIKVRQYD QVTIEICGHKVISTVLVGPTPATIIGRNLMTHLGCTLNF >7DiBV49| 3 | codons 1-99 | clone 3 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPIQICGHKVISTVLVGPTPANIIGRNLMTHLGCTLNF >7DiBV49| 4 | codons 1-99 | clone 4 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV49| 5 | codons 1-99 | clone 5 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIQEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPASIIGRNLMTQLGCTLNF >7DiBV49| 6 | codons 1-99 | clone 6 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKP.MIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV49| 7 | codons 1-99 | clone 7 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPANIIGRNLMTQLGCTLNF >7DiBV49| 9 | codons 1-99 | clone 9 PQITLWQRPIVTVRIGGQLKEALLDTGADDTVIEEINLPGRWKPKIIGGIGSFIKVRQYD QVPIEICGHKTTSTVLIGPTPVNIIGRNLMTQLGCTLNF >7DiBV49| 13 | codons 1-99 | clone 13 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV49| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |