<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
7DiBV 7DiBV49 U.S. 1994 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 49

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82A, L90M L33I, G73S L10I, I62V, L63P, A71V, V77I, I93L  
>7DiBV49| 1 | codons 1-99 | clone 1
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKVISTVLVGPTPATIIGRNLMTQLGCTLNF
>7DiBV49| 2 | codons 1-99 | clone 2
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPRRWKPKMIGGIGGFIKVRQYD
QVTIEICGHKVISTVLVGPTPATIIGRNLMTHLGCTLNF
>7DiBV49| 3 | codons 1-99 | clone 3
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKIIGGIGGFIKVRQYD
QVPIQICGHKVISTVLVGPTPANIIGRNLMTHLGCTLNF
>7DiBV49| 4 | codons 1-99 | clone 4
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF
>7DiBV49| 5 | codons 1-99 | clone 5
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIQEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKVISTVLVGPTPASIIGRNLMTQLGCTLNF
>7DiBV49| 6 | codons 1-99 | clone 6
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKP.MIGGIGGFIKVRQYD
QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF
>7DiBV49| 7 | codons 1-99 | clone 7
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKVISTVLIGPTPANIIGRNLMTQLGCTLNF
>7DiBV49| 9 | codons 1-99 | clone 9
PQITLWQRPIVTVRIGGQLKEALLDTGADDTVIEEINLPGRWKPKIIGGIGSFIKVRQYD
QVPIEICGHKTTSTVLIGPTPVNIIGRNLMTQLGCTLNF
>7DiBV49| 13 | codons 1-99 | clone 13
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF
>7DiBV49| codons 1-99
PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKVISTVLIGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005