Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 7DiBV | 7DiBV41 | U.S. | 1994 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 41 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82A, L90M | L33I, G73S | L10I, I62V, L63P, A71V, I93L |
| >7DiBV41| 21 | codons 1-99 | clone 21 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPRRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV41| 22 | codons 1-99 | clone 22 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV41| 38 | codons 1-99 | clone 38 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV41| 40 | codons 1-99 | clone 40 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLITQLGCTLNF >7DiBV41| 43 | codons 1-99 | clone 43 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV41| 46 | codons 1-99 | clone 46 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV41| 47 | codons 1-99 | clone 47 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF >7DiBV41| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |