<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
7DiBV 7DiBV19 U.S. 1994 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 19

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L90M L33I, G73S I13V, K14R, M36I, I62V, L63P, A71T, I93L  
>7DiBV19| 25 | codons 1-99 | clone 25
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEINLPGRWKPKIIGGIGGFIKVRQYD
QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF
>7DiBV19| 26 | codons 1-99 | clone 26
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKIIGGIGGFIKVRQYD
QVPIELCGHKTIGTVLIGPTPVNIIGRNLMTQLGCTLNF
>7DiBV19| 28 | codons 1-99 | clone 28
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEINLPGRWKPKIIGGIGGFIKVRQYD
QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF
>7DiBV19| 29 | codons 1-99 | clone 29
PQITLWQRPLVTIKIGGRLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKAISTVLVGPTPVNIIGRNLMTQLGCTLNF
>7DiBV19| 30 | codons 1-99 | clone 30
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF
>7DiBV19| 31 | codons 1-99 | clone 31
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKIIGGIGGFIKVRQYD
QVPIELCGHETIGTVLVGPTPVNIIGRNLMTQLGCTLNF
>7DiBV19| 33 | codons 1-99 | clone 33
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTKSTVLVGPTPVNIIGRNLMTQLGCTLNF
>7DiBV19| 34 | codons 1-99 | clone 34
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTKSTVLVGPTPVNIIGRNLMTQLGCTLNF
>7DiBV19| 36 | codons 1-99 | clone 36
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTRSTVLVGPTPVNIIGRNLMTQLGCTLNF
>7DiBV19| codons 1-99
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEINLPGRWKPKIIGGIGGFIKVRQYD
QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005