Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 7DiBV | 7DiBV19 | U.S. | 1994 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 19 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | L33I, G73S | I13V, K14R, M36I, I62V, L63P, A71T, I93L |
| >7DiBV19| 25 | codons 1-99 | clone 25 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEINLPGRWKPKIIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF >7DiBV19| 26 | codons 1-99 | clone 26 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPIELCGHKTIGTVLIGPTPVNIIGRNLMTQLGCTLNF >7DiBV19| 28 | codons 1-99 | clone 28 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEINLPGRWKPKIIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF >7DiBV19| 29 | codons 1-99 | clone 29 PQITLWQRPLVTIKIGGRLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAISTVLVGPTPVNIIGRNLMTQLGCTLNF >7DiBV19| 30 | codons 1-99 | clone 30 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF >7DiBV19| 31 | codons 1-99 | clone 31 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPIELCGHETIGTVLVGPTPVNIIGRNLMTQLGCTLNF >7DiBV19| 33 | codons 1-99 | clone 33 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTKSTVLVGPTPVNIIGRNLMTQLGCTLNF >7DiBV19| 34 | codons 1-99 | clone 34 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTKSTVLVGPTPVNIIGRNLMTQLGCTLNF >7DiBV19| 36 | codons 1-99 | clone 36 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTRSTVLVGPTPVNIIGRNLMTQLGCTLNF >7DiBV19| codons 1-99 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEINLPGRWKPKIIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |