Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 7DiBV | 7DiBV9 | U.S. | 1994 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 9 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L33I, G73S | K14R, I62V, L63P, A71T, I93L |
| >7DiBV9| 14 | codons 1-99 | clone 14 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV9| 17 | codons 1-99 | clone 17 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV9| 18 | codons 1-99 | clone 18 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV9| 24 | codons 1-99 | clone 24 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV9| 25 | codons 1-99 | clone 25 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV9| 26 | codons 1-99 | clone 26 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV9| 29 | codons 1-99 | clone 29 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV9| 30 | codons 1-99 | clone 30 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF >7DiBV9| 31 | codons 1-99 | clone 31 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF >7DiBV9| 32 | codons 1-99 | clone 32 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF >7DiBV9| codons 1-99 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |