<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
7DiBV 7DiBV6 U.S. 1993 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 6

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33I K14R, I62V, L63P, A71T, I93L  
>7DiBV6| 41 | codons 1-99 | clone 41
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV6| 42 | codons 1-99 | clone 42
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPINIIGRNLLTQLGCTLNF
>7DiBV6| 43 | codons 1-99 | clone 43
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEFCGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV6| 44 | codons 1-99 | clone 44
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVIKEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIELCGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV6| 46 | codons 1-99 | clone 46
PQITLWQQPLVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF
>7DiBV6| 47 | codons 1-99 | clone 47
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQLGCTLNF
>7DiBV6| 48 | codons 1-99 | clone 48
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTISTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV6| 49 | codons 1-99 | clone 49
PQITLWQRPLITVRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTISTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV6| 50 | codons 1-99 | clone 50
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRSLLTQLGCTLNF
>7DiBV6| 51 | codons 1-99 | clone 51
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV6| 52 | codons 1-99 | clone 52
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV6| codons 1-99
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005