Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 7DiBV | 7DiBV2 | U.S. | 1993 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 2 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33I | K14R, I62V, L63P, A71T, I93L | E65R |
| >7DiBV2| 12 | codons 1-99 | clone 12 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV2| 28 | codons 1-99 | clone 28 PQITLWQRPLATIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV2| 29 | codons 1-99 | clone 29 PQITLWQRPLVTIRIGGQLKEALLDTGANDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV2| 30 | codons 1-99 | clone 30 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGSVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV2| 31 | codons 1-99 | clone 31 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIRICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV2| 34 | codons 1-99 | clone 34 PQITLWQRPLVTIRIGGQLKEALLHTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV2| 35 | codons 1-99 | clone 35 PQITLWQRPLVTIRIGGQLKEALLHTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF >7DiBV2| codons 1-99 PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD QVPIRICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |