<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
7DiBV 7DiBV2 U.S. 1993 HIV1 B Plasma MMC

Treatment History
Order Regimen Weeks
1 NRTI+IDV 2

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33I K14R, I62V, L63P, A71T, I93L E65R
>7DiBV2| 12 | codons 1-99 | clone 12
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV2| 28 | codons 1-99 | clone 28
PQITLWQRPLATIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV2| 29 | codons 1-99 | clone 29
PQITLWQRPLVTIRIGGQLKEALLDTGANDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV2| 30 | codons 1-99 | clone 30
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGSVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV2| 31 | codons 1-99 | clone 31
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIRICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV2| 34 | codons 1-99 | clone 34
PQITLWQRPLVTIRIGGQLKEALLHTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV2| 35 | codons 1-99 | clone 35
PQITLWQRPLVTIRIGGQLKEALLHTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF
>7DiBV2| codons 1-99
PQITLWQRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD
QVPIRICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Zhang, Y-M Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. J Virol, 1997
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005