Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK2109 | UK2109 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ ABC | 31 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, G16E, L19I, M36I, R41K, D60E, H69K, V82I, L89M, I93L |
| >UK2109| codons 1-99 PQITLWQRPLVSIKVEGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K20R, V35T, T39E, K43KR, S48T, K104R, K122E, D123N, I135T, E138A, K173I, Q174K, I195IM, T200A, E203EK, Q207E, L210LM, R211K, F214L |
| >UK2109| codons 1-234 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEREGKITKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPDIVI YQYVDDLYVGSDLEMGQHRAKIKELREHLMKWGLTTPDKKHQKEPPFLWMGYEL |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |