Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK1673c | UK1673c | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV+ 3TC+ AZT | 65 |
| 2 | DDI+ LPV+ D4T | 13 |
| 3 | EFV+ D4T+ DDI | 32 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N, G190GA | P225PH | V35T, T39E, S48T, K122E, K173A, D177E, T200A, Q207E, R211K |
| >UK1673c| codons 1-234 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYMDDLYVASDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEHPFLWMGYEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, H69K, L89M, I93L |
| >UK1673c| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |