Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK2088 | UK2088 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTV+ 3TC+ AZT | NA |
| 2 | 3TC+ 3TC+ AZT | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82F | I13V, K14R, I15V, K20R, E35D, M36I, R41K, I62V, L63LP, H69K, T74TS, L89I | L97LS |
| >UK2088| codons 1-99 PQITLWQRPLVTVRVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QVPIEICGKKAIGSVLVGPTPFNIIGRNILTQIGCTSNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | K11T, K20R, V21I, V35T, T39G, V60I, K122E, D123N, I135T, E138A, I142V, K173S, D177E, V179I, T200A, I202V, Q207A |
| >UK2088| codons 1-234 PISPIETVPVTLKPGMDGPRIKQWPLTEEKIKALTEICGELEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNATPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPEIII YQYVDDLYVGSDLEIGQHRAKVEELRAHLWRWGFYTPDKKHQKEPPFLWMGYEL |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |