Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK2069 | UK2069 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC+ DDI+ D4T+ AZT | NA |
| 2 | NFV+ D4T+ 3TC | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | F116Y | G190A | K20R, V35T, E36A, T39E, V111I, K122E, D123N, A158S, K173A, D177E, T200A, R211K, F214C | N57Y, Q222QH |
| >UK2069| codons 1-227 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYYTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDIGDAYYSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPSIFQSSMTKILEPFRAQNPEIVI YQYVDDLYVASDLEIGQHRAKIEELRQHLLKWGCTTPDKKHHKEPPF |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | T12S, I13V, I15V, Q18H, L19I, K20R, E35D, M36I, R41K, L63V, H69K, T74S, L89I, I93L |
| >UK2069| codons 1-99 PQITLWQRPLVSVKVGGHIREALLDTGADNTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIVIEICGKKAIGSVLVGPTPVNIIGRDILTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |