Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK2062 | UK2062 | U.K. | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 30 |
| 2 | IDV+ 3TC+ Unknown | NA |
| 3 | DDC+ EFV+ Unknown | NA |
| 4 | NVP+ D4T+ 3TC | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | E28K, K32E, V35T, E36A, T39E, S68SN, K122E, D123S, I135T, S162C, E169EA, K173A, D177E, T200A, Q207E |
| >UK2062| codons 1-234 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTAICEEMEKEGKISKIGPENPYNTPV FAIKKKDNTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILAPFRAQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12TS, I15V, L19IV, M36I, L63P, I64L, H69K, I93L |
| >UK2062| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QIPLEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |