Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 6HeBV | 6HeBV44 | U.S. | 1994 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+IDV | 44 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | L10I, I15V, L63P, K70Q |
| >6HeBV44| 37 | codons 1-99 | clone 37 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLMTQIGCTLNF >6HeBV44| 38 | codons 1-99 | clone 38 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLMTQIGCTLNF >6HeBV44| 39 | codons 1-99 | clone 39 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNMLTQIGCTLNF >6HeBV44| 40 | codons 1-99 | clone 40 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNMLTQIGCTLNF >6HeBV44| 41 | codons 1-99 | clone 41 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVR*YD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV44| 42 | codons 1-99 | clone 42 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRRYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV44| 43 | codons 1-99 | clone 43 PQITLRQRPIVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV44| 44 | codons 1-99 | clone 44 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLLTQIGCTLNF >6HeBV44| 45 | codons 1-99 | clone 45 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNMLTQIGCTLNF >6HeBV44| 46 | codons 1-99 | clone 46 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNMLTQIGCTLNF >6HeBV44| codons 1-99 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHQAIGTVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Zhang, Y-M | Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its gag substrate cleavage sites. | J Virol, 1997 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |