Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK1988 | UK1988 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV+ DDI+ D4T | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74LV | K101KE, K103N, V106VM, G190GRS | V35T, E36A, T39E, S48E, K122E, D123NS, E169K, K173E, D177E, T200A, E203EK |
| >UK1988| codons 1-235 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKIEKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKNKSMTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILKPFREQNPEIVI YQYMDDLYVSSDLEIGQHRAKIKELRQHLLRWGFTTPDKKHQKEPPFLWMGYELH |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, R41K, K45R, I62V, L63T, I64L, H69K, A71T, V77VI, I93L |
| >UK1988| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDMNLPGKWKPRMIGGIGGFIKVRQYD QVTLEICGKKTIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |