Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK1461b | UK1461b | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ NFV | 35 |
| 2 | TDF+ NVP+ ABC | 49 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90LM | L23I | T12S, I15V, L19I, K20T, E35D, M36I, R41K, D60E, H69K, V82I, L89M, I93L |
| >UK1461b| codons 1-99 PQITLWQRPLVSIKVGGQITEAILDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPINIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, Y115F, M184V | Y181C | V21VI, V35T, T39E, K122E, D123N, I135T, K173A, D177E, T200A, E204K, Q207E, R211K, F214L, H221HY |
| >UK1461b| codons 1-234 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAFFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI CQYVDDLYVGSDLEIGQHRAKIEKLREHLLKWGLTTPDKKYQKEPPFLWMGYEL |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |