Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK1972 | UK1972 | U.K. | 2001 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | NA |
| 2 | NVP+ D4T+ 3TC | 211 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, M36I, R41K, L63Q, I64V, E65D |
| >UK1972| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIQVDICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, T215Y | G190A | K32I, L34I, V35T, T39A, K49R, K104KR, S117A, S162CY, S163ST, D177E, I178F, T200R, Q207E, H208Y, R211K, W212R, H221Y |
| >UK1972| codons 1-230 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIIAITEICAELEKEGKISRIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFAVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYTMTKILEPFRKQNPEFVI YQYVDDLYVASDLEIGQHRRKIEELREYLLKRGFYTPDKKYQKEPPFLWM |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |